The Nash Ambassador received a complete restyle for 1952 and celebrated the automaker's 50th anniversary as the predecessor firm, the Thomas B. Jeffery Company, marketed its first cars in 1902.[52]

The Golden Anniversary Nash Airflyte featured styling publicly credited to Pininfarina. Yet, the design was a combination of the Italian coachbuilder with ideas from Edmund E. Anderson, the lead designer at Nash.[53] The new cars had more conventional lines than the previous 1949 through 1951 Ambassadors and they received several design awards.[52] The large "envelope-bodied" sedans followed the pattern of Nash's enclosed wheels along with now larger die cast "toothy" grille bars.[54] Several European touches were incorporated into production such as the reverse-slanted C-pillars and an interior fishnet "parcel holder" mounted above the windshield for keeping maps and sunglasses.[54] Nash claimed that the Ambassador's comfort and luxury features were so advanced "that other new cars seem outdated in comparison" and advertised the Ambassador as having the broadest and most comfortable seating.[52] The 1952 unit-body design "were good-looking notchbacks" that "looked like nothing on the road," and the cars continued into 1954, almost unchanged.[54][53] The 1955 models received a revised front grille with integral headlamps. The rear end was redesigned with more pronounced tailfins for 1956, while the final year saw a new front end with "quad" headlamps or two stacked headlamps per side.