The third-generation Jeep Grand Cherokee (WK) is a mid-size SUV that was manufactured and marketed by Jeep from the 2005 to the 2010 model years. It was unveiled at the 2004 New York International Auto Show and subsequently in Europe at Euro Camp Jeep in Ardèche, France.

Major features included Quadra-Drive II four-wheel drive, rear-seat DVD player, and optional 5.7 L Hemi V8 engine. The 3.7 L V6 engine replaced the 4.0 L straight-6engine. Notably, the WK featured independent front suspension.

In 2008, the WK received a minor facelift with revised headlights and high intensity discharge (HID) Headlamps with auto leveling. The lower portion of the front bumper became removable to increase the approach angle for off-road use. The 4.7 L was refined, now producing 305 hp (227 kW; 309 PS), and 334 lb⋅ft (453 N⋅m).

The 2009 Jeep Grand Cherokee was available with an improved 5.7 L Hemi enginerated at 360 hp (268 kW; 365 PS) and 390 lb⋅ft (529 N⋅m) of torque. The engine uses variable valve timing to increase fuel economy.