Kabushiki-Kaisha), commonly known as Isuzu (Japanese pronunciation: [isɨᵝzɨᵝ], /iˈsuzu,aɪ-/), is a Japanese multinational automobile manufacturer headquartered in Yokohama, Kanagawa Prefecture. Its principal activity is the production, marketing and sale of Isuzu commercial vehicles and diesel engines. The company also has a number of subsidiaries and joint ventures, including UD Trucks, Anadolu Isuzu (a Turkish joint venture with Anadolu Group), Sollers-Isuzu (a Russian joint venture with Sollers JSC - Production stopped in March 2022, Isuzu stake transferred to Sollers in July 2023[2]), SML Isuzu (an Indian venture formerly known as Swaraj Mazda), Jiangxi Isuzu Motors (a Chinese joint venture with Jiangling Motors Company Group), Isuzu Astra Motor Indonesia, Isuzu Malaysia (Isuzu HICOM), Industries Mécaniques Maghrébines, Isuzu Truck (UK), Isuzu South Africa, Isuzu Philippines, Taiwan Isuzu Motors, Isuzu Vietnam, Isuzu Motors India and BYD Isuzu.

Isuzu has assembly and manufacturing plants in Fujisawa, which have been there since the company was founded under earlier names, as well as in the Tochigi and Hokkaidoprefectures. Isuzu-branded vehicles are sold in most commercial markets worldwide. Isuzu's primary market focus is on commercial diesel-powered truck, buses and construction.